Researchers from Luxembourg have presented a method to optimize pulsatile flows in microfluidic experiments using two commercial pressure pumps. They analyzed the linear response of the systems to a sinusoidal pressure input and derived an adapted input signal. They demonstrated that this adapted pressure input leads to an enhancement of the time-dependent flow of red blood cells in microchannels.
The above method does not rely on any hardware modifications and can be easily implemented in standard pressure-driven microfluidic setups to generate accurate pulsatile flows with arbitrary waveforms.
Source: Optimizing pressure-driven pulsatile flows in microfluidic devices
