Source: MIT News
This demonstration from MIT shows microfluidic circuits created by micromilling Lego and connecting them together to form various circuits. Among other things they have created mixers and droplet generators that generate droplets at > 150Hz. They have also successfully managed to sort cells and filter out specific molecules. They fabricated channels as small as 50µm deep and 150µm wide which were then sealed with adhesive films.
This research from MIT’s Laboratory for Manufacturing and Productivity and the Mechanosynthesis Group is extremely interesting and definitely worth checking out.
Press Release: MIT News
Research Paper: High-precision modular microfluidics by micromilling of interlocking injection-molded blocks