Continuous disease monitoring and in-vivo drug screening using microfluidics

Schematic of the delivery sampling probe
Source: Antoine Barbot, Dominic Wales, Eric Yeatman, Guang‐Zhong Yang, Microfluidics at Fiber Tip for Nanoliter Delivery and Sampling

This paper describes a microfluidic design that uses a passive valve mechanism to create 10nl sized droplets. These are then used for droplet based liquid biopsies. Applications include facilitating liquid biopsies for continuous disease monitoring and in-vivo drug screening.

Source: Antoine Barbot, Dominic Wales, Eric Yeatman, Guang‐Zhong Yang, Microfluidics at Fiber Tip for Nanoliter Delivery and Sampling